Hihara H., Tagaino R., Washio J., Laosuwan K., Wicaksono D.P., Izumita K., Koide R., Takahashi N., Sasaki K.
Division of Advanced Prosthetic Dentistry, Tohoku University Graduate School of Dentistry, 4-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8575, Japan; Division of Oral Ecology and Biochemistry, Tohoku University Graduate School of Dentistry, Sendai, Miyagi, Japan; Department of Oral Biology and Oral Diagnostic Sciences, Faculty of Dentistry, Chiang Mai University, T. Suthep, A. Muang, Chiang Mai, 50200, Thailand; Faculty of Dental Medicine, Department of Pediatric Dentistry, Universitas Airlangga, St. Mayjen Prof. Dr. Moestopo No. 47, Surabaya, 60132, Indonesia
Background: Removal of oral biofilm from the oral mucosa is essential for preventing risk of respiratory and gastrointestinal infection in elderly people. Currently, no device is available which can remove oral biofilm from oral mucosa effectively and safely. Therefore, the effectiveness and safety of the Micro Scale Mist UNIT (MSM-UNIT), a newly developed dental plaque removal device utilizing high speed sprays of fine water droplets, were evaluated for biofilm removal, including the rate and surface roughness for simulated tooth surface and mucous membrane. Methods: Simulated tooth and oral mucosa coated with an artificial biofilm of Streptococcus mutans were used for evaluation of effectiveness, with uncoated substrates as the controls. The MSM-UNIT and a conventional air ablation device were operated under recommended instructions. The effectiveness was evaluated from the rate of removal of the biofilm, and the safety was evaluated from the damage observed by scanning electron microscope and surface roughness. Results: The biofilm removal rate of the MSM-UNIT was significantly higher than that of AIRFLOW. Little damage was observed in the area treated by the MSM-UNIT. The surface roughness of the MSM-UNIT treated area on simulated tooth surface and oral mucosa showed no significant difference to the control area. In contrast, cracks and powder were observed in the area treated by AIRFLOW. In particular, the surface roughness of the AIRFLOW treated area for Toughsilon was significantly larger than that of the control. Conclusions: The MSM-UNIT could be used safely and effectively for removing biofilm not only on simulated tooth surfaces but also simulated mucous membrane. The MSM-UNIT has no harmful effect on teeth or oral mucosa, and may be used for comprehensive oral care for patients during nursing care and the perioperative period. © 2021, The Author(s).
Micro scale mist; Oral biofilm; Oral care; Oral mucosa; Translational research
BMC Oral Health
Publisher: BioMed Central Ltd
Volume 21, Issue 1, Art No 286, Page – , Page Count
Journal Link: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85107331515&doi=10.1186%2fs12903-021-01647-4&partnerID=40&md5=1d3b2859c22fe872d85bd5871dc63e4d
Type: All Open Access, Gold, Green
Nyvad, B., Takahashi, N., Integrated hypothesis of dental caries and periodontal diseases (2020) J Oral Microbiol, 12 (1), p. 1710953; Hua, F., Xie, H., Worthington, H.V., Furness, S., Zhang, Q., Li, C., Oral hygiene care for critically ill patients to prevent ventilator-associated pneumonia (2016) Cochrane Database Syst Rev, 10 (10), p. CD008367. , PID: 27778318; Sjögren, P., Wårdh, I., Zimmerman, M., Almståhl, A., Wikström, M., Oral care and mortality in older adults with pneumonia in hospitals or nursing homes: Systematic review and meta-analysis (2016) J Am Geriatr Soc, 64 (10), pp. 2109-2115; Yoneyama, T., Yoshida, M., Ohrui, T., Mukaiyama, H., Okamoto, H., Hoshiba, K., Oral Care Working Group. Oral care reduces pneumonia in older patients in nursing homes (2002) J Am Geriatr Soc, 50 (3), pp. 430-433; Shigeishi, H., Ohta, K., Fujimoto, S., Nakagawa, T., Mizuta, K., Ono, S., Preoperative oral health care reduces postoperative inflammation and complications in oral cancer patients (2016) Exp Ther Med, 12 (3), pp. 1922-1928; Liu, C., Cao, Y., Lin, J., Ng, L., Needleman, I., Walsh, T., Oral care measures for preventing nursing home-acquired pneumonia (2018) Cochrane Database Syst Rev, 9 (9), p. CD012416. , PID: 30264525; Kaneoka, A., Pisegna, J.M., Miloro, K.V., Lo, M., Saito, H., Riquelme, L.F., Prevention of healthcare-associated pneumonia with oral care in individuals without mechanical ventilation: a systematic review and meta-analysis of randomized controlled trials (2015) Infect Control Hosp Epidemiol, 36 (8), pp. 899-906; de Lacerda Vidal, C.F., Vidal, A.K., Monteiro, J.G., Jr., Cavalcanti, A., Henriques, A.P.C., Oliveira, M., Impact of oral hygiene involving toothbrushing versus chlorhexidine in the prevention of ventilator-associated pneumonia: a randomized study (2017) BMC Infect Dis, 17 (1), p. 112; Aas, J.A., Paster, B.J., Stokes, L.N., Olsen, I., Dewhirst, F.E., Defining the normal bacterial flora of the oral cavity (2005) J Clin Microbiol, 43 (11), pp. 5721-5732; Ogasawara, T., Kawase, Y., Isono, K., Okada, Y., Hashima, H., Shen, F.C., Formative factors of membranous substances on dorsum of tongue, teeth, buccal mucosa in elderly persons requiring nursing care (2014) Jpn J Geriatrics, 29 (1), p. 1120. , in Japanese; Kawase, Y., Ogasawara, T., Kawase, S., Wakimoto, N., Matsuo, K., Shen, F.C., Factors affecting the formation of membranous substances in the palates of elderly persons requiring nursing care (2014) Gerodontology, 31 (3), pp. 184-193; Shen, F.C., Ogasawara, T., Shinotsuka, K., Miyahara, K., Isono, K., Mochiduki, N., Matsumura, K., Histopathological evaluation of oral membranous substance in bedridden elderly persons without oral intake in Japan (2019) Gerodontology, 36 (1), pp. 63-70; Kato, K., Tamura, K., Nakagaki, H., Quantitative evaluation of the oral biofilm-removing capacity of a dental water jet using an electron-probe microanalyzer (2012) Arch Oral Biol, 57 (1), pp. 30-35; Weaks, L.M., Lescher, N.B., Barnes, C.M., Holroyd, S.V., Clinical evaluation of the Prophy-Jet® as an instrument for routine removal of tooth stain and plaque (1984) J Periodontol, 55 (8), pp. 486-488; Petersilka, G.J., Tunkel, J., Barakos, K., Heinecke, A., Häberlein, I., Flemmig, T.F., Subgingival plaque removal at interdental sites using a low-abrasive air polishing powder (2003) J Periodontol, 74 (3), pp. 307-311; Petersilka, G.J., Steinmann, D., Häberlein, I., Heinecke, A., Flemmig, T.F., Subgingival plaque removal in buccal and lingual sites using a novel low abrasive air-polishing powder (2003) J Clin Periodontol, 30 (4), pp. 328-333; Petersilka, G.J., Faggion, C.M., Jr., Stratmann, U., Gerss, J., Ehmke, B., Haeberlein, I., Effect of glycine powder air-polishing on the gingiva (2008) J Clin Periodontol, 35 (4), pp. 324-332; Moëne, R., Dècaillet, F., Andersen, E., Mombelli, A., Subgingival plaque removal using a new air-polishing device (2010) J Periodontol, 81 (1), pp. 79-88; Flemmig, T.F., Hetzel, M., Topoll, H., Gerss, J., Haeberlein, I., Petersilka, G., Subgingival debridement efficacy of glycine powder air polishing (2007) J Periodontol, 78 (6), pp. 1002-1010; Uehara, S., Nakajima, T., Moriya, S., Maruyama, S., Sato, T., Removal mechanism of artificial dental plaque by impact of micro-droplets (2019) ECS J Solid State Sci Technol, 8 (2), pp. N20-4; Hosono, Y., Sato, Y., Kitagawa, N., Shimodaira, N., Hara, S., Assessment of biomechanical characteristic of denture supporting tissue using an ultrasonic thickness gage and a tactile sensor (2007) J Jpn Prosthodont Soc, 51 (2), pp. 291-299. , in Japanese; Manome, A., Abiko, Y., Kawashima, J., Washio, J., Fukumoto, S., Takahashi, N., Acidogenic potential of oral bifidobacterium and its high fluoride tolerance (2019) Front Microbiol, 10, p. 1099; Kameda, M., Abiko, Y., Washio, J., Tanner, A.C.R., Kressirer, C.A., Mizoguchi, I., Takahashi, N., Sugar metabolism of Scardovia wiggsiae, a novel caries-associated bacterium (2020) Front Microbiol, 11, p. 479; Ohashi, A., Harada, H., Adhesion strength of biofilm developed in an attached-growth receptor (1994) Water Sci Technol, 29 (10-11), pp. 281-288; Stoodley, P., Cargo, R., Rupp, C.J., Wilson, S., Klapper, I., Biofilm material properties as related to shear-induced deformation and detachment phenomena (2002) J Ind Microbiol Biotechnol, 29 (6), pp. 361-367; Rmaile, A., Carugo, D., Capretto, L., Aspiras, M., De Jager, M., Ward, M., Removal of interproximal dental biofilms by high-velocity water microdrops (2014) J Dent Res, 93 (1), pp. 68-73; Salerno, C., Pascale, M., Contaldo, M., Esposito, V., Busciolano, M., Milillo, L., Candida-associated denture stomatitis (2011) Med Oral Pathol Oral Cir Bucal, 16 (2), pp. e139-43; Yonezawa, H., Takasaki, K., Teraoka, K., Asaka, T., Sato, C., Tsuchiya, K., Effects of tongue and oral mucosa cleaning on oral Candida species and production of volatile sulfur compounds in the elderly in a nursing home (2003) J Med Dent Sci, 50 (1), pp. 1-8. , PID: 12715913; Yadav, S.R., Kini, V.V., Padhye, A., Inhibition of tongue coat and dental plaque formation by stabilized chlorine dioxide vs chlorhexidine mouthrinse: a randomized, triple blinded study (2015) J Clin Diagn Res, 9 (9), pp. ZC69-74. , PID: 26501017; Tashiro, K., Katoh, T., Yoshinari, N., Hirai, K., Andoh, N., Makii, K., The short-term effects of various oral care methods in dependent elderly: comparison between toothbrushing, tongue cleaning with sponge brush and wiping on oral mucous membrane by chlorhexidine (2012) Gerodontology, 29 (2), pp. e870-82; James, P., Worthington, H.V., Parnell, C., Harding, M., Lamont, T., Cheung, A., Chlorhexidine mouthrinse as an adjunctive treatment for gingival health (2017) Cochrane Database Syst Rev, 3 (3), p. CD008676. , PID: 28362061; Jablonowski, L., Fricke, K., Matthes, R., Holtfreter, B., Schlüter, R., von Woedtke, T., Removal of naturally grown human biofilm with an atmospheric pressure plasma jet: an in-vitro study (2017) J Biophotonics, 10 (5), pp. 718-726; Nishikawa, T., Yoshida, A., Khanal, A., Habu, M., Yoshioka, I., Toyoshima, K., A study of the efficacy of ultrasonic waves in removing biofilms (2010) Gerodontology, 27 (3), pp. 199-206; Howlin, R.P., Fabbri, S., Offin, D.G., Symonds, N., Kiang, K.S., Knee, R.J., Removal of dental biofilms with an ultrasonically activated water stream (2015) J Dent Res, 94 (9), pp. 1303-1309; Bühler, J., Amato, M., Weiger, R., Walter, C., A systematic review on the patient perception of periodontal treatment using air polishing devices (2016) Int J Dent Hyg, 14 (1), pp. 4-14; Flemmig, T.F., Arushanov, D., Daubert, D., Rothen, M., Mueller, G., Leroux, B.G., Randomized controlled trial assessing efficacy and safety of glycine powder air polishing in moderate-to-deep periodontal pockets (2012) J Periodontol, 83 (4), pp. 444-452; Cobb, C.M., Daubert, D.M., Davis, K., Deming, J., Flemmig, T.F., Pattison, A., Consensus conference findings on supragingival and subgingival air polishing (2017) Compend Contin Educ Dent, 38 (2), pp. e1-e4
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