Wardojo S.S.I., Huang Y.-L., Chuang K.-Y.
School of Public Health, Taipei Medical University, Taipei, Taiwan; Faculty of Health Science, University of Muhammadiyah, Malang, Indonesia; Department of Public Health, School of Medicine, College of Medicine, Taipei Medical Univeristy, Taipei, Taiwan
Background: As the number of people living with human immunodeficiency virus (HIV; PLHIV) in Indonesia has increased in recent years, more efforts have been expended to improve their health status. However, in a country where PLHIV are very much stigmatized, there has been little research concerning their quality of life (QoL). Hence, this study aimed to assess the QoL among PLHIV and its associated factors. Findings of this research can contribute to improving the health and wellbeing of PLHIV in Indonesia. Methods: A cross-sectional survey with convenience sampling was conducted from June to September 2018, at four healthcare centers in Malang, Indonesia. PLHIV, aged 18 years or over, were asked if they would like to participate in this study when they came to a health center to receive services. To protect confidentiality, the healthcare staff at the clinics assisted with recruitment and face-to-face interviews with structured questionnaires. Measurements included sociodemographic, medication-related, social support, HIV-stigma, and QoL variables. Results: In total, 634 PLHIV agreed to participate in this study. A multivariate linear regression analysis showed that being older, having a job, living in an urban area, having better access to healthcare services, adhering to medication, being in an antiretroviral therapy (ART) program for more than 1 year, experiencing a lower level of stigma, and receiving more social support were associated with a better QoL. The regression model had an adjusted R2 of 0.21. Conclusions: Findings from this research have significant policy implications. Policies focused on reducing social stigma and promoting medication adherence will likely have a positive impact on the QoL of PLHIV. Increasing public awareness and acceptance of PLHIV in Indonesia remains challenging, but would likely have significant impacts. Furthermore, interventions should also focus on reducing disparities in QoL between PLHIV living in rural areas and those in urban areas. © 2021, The Author(s).
ART adherence; HIV; QoL; Stigma
BMC Public Health
Publisher: BioMed Central Ltd
Volume 21, Issue 1, Art No 1272, Page – , Page Count
Journal Link: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85108997673&doi=10.1186%2fs12889-021-11321-7&partnerID=40&md5=1336489e794e54d2206d1a39d2909545
Type: All Open Access, Gold, Green
Kemenkes, R.I., (2020) Infodatin HIV AIDS. Kesehatan., pp. 1-8. , http://www.depkes.go.id/resources/download/pusdatin/infodatin/InfodatinAIDS.pdf; Demartoto, A., Murti, B., Zunariyah, S., HIV/AIDS treatment funding system to support the people affected by HIV/AIDS in Surakarta, Indonesia (2021) SAHARA-J J Soc Asp HIV/AIDS, 18 (1), pp. 1-16; (2017) Program Pengendalian HIV AIDS dan PIMS Fasilitas Kesehatan Tingkat Pertama, pp. 1-109. , Direktur Jenderal P2P Kementrian Kesehatan RI; Penyakit Menular Seksual (2020) Jakarta Indonesia, , https://siha.kemkes.go.id/portal/files_upload/Laporan_Perkembangan_HIV_AIDS_dan_PIMS_Triwulan_III_Tahun_2020.pdf; Januraga, P.P., Mooney-Somers, J., Ward, P.R., Newcomers in a hazardous environment: a qualitative inquiry into sex worker vulnerability to HIV in Bali, Indonesia (2014) BMC Public Health, 14 (1), p. 832; Riono, P., Challacombe, S.J., HIV in Indonesia and in neighbouring countries and its social impact (2020) Oral Dis, 26 (S1), pp. 28-33; Waluyo, A., Culbert, G.J., Levy, J., Norr, K.F., Understanding HIV-related stigma among Indonesian nurses (2015) J Assoc Nurses AIDS Care, 26 (1), pp. 69-80; Supriyadi, M.T., Yuliana, F., The disjunction between policy and practice: HIV discrimination in health care and employment in Indonesia (2005) AIDS Care, 17, pp. 37-41; Wisaksana, R., Alisjahbana, B., van Crevel, R., Kesumah, N., Sudjana, P., Sumantri, R., Challenges in delivering HIV-care in Indonesia: experience from a referral hospital (2009) Acta Med Indones, 41, pp. 45-51. , PID: 19920298; Basavaraj, K.H., Navya, M.A., Rashmi, R., Quality of life in HIV/AIDS (2010) Indian J Sex Transm Dis AIDS, 31 (2), pp. 75-80; (2002) Whoqol-Hiv Bref Mental Health: Evidence and Research Department of Mental Health World Health Organization.Geneva, , https://www.who.int/mental_health/publications/whoqol_hiv_bref.pdf; Briongos Figuero, L.S., Bachiller Luque, P., Palacios Martín, T., González Sagrado, M., Eiros Bouza, J.M., Assessment of factors influencing health-related quality of life in HIV-infected patients (2011) HIV Med, 12 (1), pp. 22-30; Protopopescu, C., Raffi, F., Roux, P., Reynes, J., Dellamonica, P., Spire, B., Factors associated with non-adherence to long-term highly active antiretroviral therapy: a 10 year follow-up analysis with correction for the bias induced by missing data (2009) J Antimicrob Chemother, 64 (3), pp. 599-606. , (,):., https://doi.org/10.1093/jac/dkp232; Gibson, K., Rueda, S., Rourke, S.B., Bekele, T., Gardner, S., Fenta, H., Mastery and coping moderate the negative effect of acute and chronic stressors on mental health-related quality of life in HIV (2011) AIDS Patient Care STDs, 25 (6), pp. 371-381. , (,):., https://doi.org/10.1089/apc.2010.0165; George, S., Bergin, C., Clarke, S., Courtney, G., Codd, M.B., Health-related quality of life and associated factors in people with HIV: an Irish cohort study (2016) Health Qual Life Outcomes, 14 (1), pp. 1-12; Mekuria, L.A., Sprangers, M.A.G., Prins, J.M., Yalew, A.W., Nieuwkerk, P.T., Health-related quality of life of HIV-infected adults receiving combination antiretroviral therapy in Addis Ababa (2015) AIDS Care, 27 (8), pp. 934-945; Nobre, N., Pereira, M., Roine, R.P., Sintonen, H., Sutinen, J., Factors associated with the quality of life of people living with HIV in Finland (2017) AIDS Care, 29 (8), pp. 1074-1078; Monteiro, F., Canavarro, M.C., Pereira, M., Factors associated with quality of life in middle-aged and older patients living with HIV (2016) AIDS Care, 28 (March), pp. 92-98; Passos, S.M.K., Souza LD de, M., An evaluation of quality of life and its determinants among people living with HIV/AIDS from southern Brazil (2015) Cad Saude Publica, 31 (4), pp. 800-814; Ferlatte, O., Salway, T., Oliffe, J.L., Trussler, T., Stigma and suicide among gay and bisexual men living with HIV (2017) AIDS Care, 29 (11), pp. 1346-1350; Koirala, S., Deuba, K., Nampaisan, O., Marrone, G., Ekström, A.M., Satti, A., Facilitators and barriers for retention in HIV care between testing and treatment in Asia- a study in Bangladesh, Indonesia, Lao, Nepal, Pakistan, Philippines, and Vietnam (2017) PLoS One, 12, pp. 1-20; Geocze, L., Mucci, S., de Marco, M.A., Nogueira-Martins, L.A., de Albuquerque Citero, V., Quality of life and adherence to HAART in HIV-infected patients (2010) Rev Saude Publica, 44 (4), pp. 743-749; Rueda, S., Raboud, J., Mustard, C., Bayoumi, A., Lavis, J.N., Rourke, S.B., Employment status is associated with both physical and mental health quality of life in people living with HIV (2011) AIDS Care, 23 (4), pp. 435-443; O’Brien, N., Greene, S., Carter, A., Lewis, J., Nicholson, V., Kwaramba, G., Envisioning women-centered HIV care: perspectives from women living with HIV in Canada (2017) Womens Heal Issues, 27 (6), pp. 721-730; Herrmann, S., McKinnon, E., Hyland, N.B., Lalanne, C., Mallal, S., Nolan, D., HIV-related stigma and physical symptoms have a persistent influence on health-related quality of life in Australians with HIV infection (2013) Health Qual Life Outcomes, 11 (56). , http://www.hqlo.com/content/11/1/56%5Cnhttp://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=reference&D=emed11&NEWS=N&AN=2013238859; Lindayani, L., Chen, Y.C., Der Wang, J., Ko, N.Y., Complex problems, care demands, and quality of life among people living with HIV in the antiretroviral era in Indonesia (2018) J Assoc Nurses AIDS Care., 29 (2), pp. 300-309; Annual Progress Report (2019) Annu Prog Rep, , https://dinkes.malangkota.go.id/wp-content/uploads/sites/104/2019/09/LAKIP-2018.pdf; Lindayani, L., Ibrahim, K., Der Wang, J., Ko, N.Y., Independent and synergistic effects of self- and public stigmas on quality of life of HIV-infected persons (2018) AIDS Care, 30 (6), pp. 706-713; Garrido-Hernansaiz, H., Heylen, E., Bharat, S., Ramakrishna, J., Ekstrand, M.L., Stigmas, symptom severity and perceived social support predict quality of life for PLHIV in urban Indian context (2016) Health Qual Life Outcomes, 14 (1), p. 152; Canavarro, M.C., Pereira, M., AIDS care: Psychological and socio-medical aspects of AIDS / HIV factor structure and psychometric properties of the European Portuguese version of a questionnaire to assess quality of life in HIV-infected adults: The (2012) AIDS Care, 2012, pp. 799-807. , https://www.tandfonline.com/doi/abs/https://doi.org/10.1080/09540121.2011.630362; Hsiung, P.C., Fang, C.T., Wu, C.H., Sheng, W.H., Chen, S.C., Der Wang, J., Validation of the WHOQOL-HIV BREF among HIV-infected patients in Taiwan (2011) AIDS Care, 23 (8), pp. 1035-1042; Saddki, N., Noor, M.M., Norbanee, T.H., Rusli, M.A., Norzila, Z., Zaharah, S., Validity and reliability of the Malay version of WHOQOL-HIV BREF in patients with HIV infection (2009) AIDS Care, 21 (10), pp. 1271-1278. , (,):., https://doi.org/10.1080/09540120902803216; Pujasari, H., Levy, J., Culbert, G., Steffen, A., Carley, D., Kapella, M., Sleep disturbance, associated symptoms, and quality of life in adults living with HIV in Jakarta, Indonesia (2021) AIDS Care, 33 (1), pp. 39-46. , (,):., https://doi.org/10.1080/09540121.2020.1748868; Zimet, G.D., Dahlem, N.W., Zimet, S.G., Gordon, K., Farley, G.K., The multidimensional scale of perceived social support the multidimensional scale of perceived social support (2010) J Pers Assess, 52, pp. 37-41; Laksmita, O.D., Chung, M.-H., Liao, Y.-M., Chang, P.-C., Multidimensional scale of perceived social support in Indonesian adolescent disaster survivors: a psychometric evaluation (2020) PLoS One, 15 (3); Reinius, M., Wettergren, L., Wiklander, M., Svedhem, V., Ekström, A.M., Eriksson, L.E., Development of a 12-item short version of the HIV stigma scale (2017) Health Qual Life Outcomes, 15, pp. 1-9; Berger, B.E., Ferrans, C.E., Lashley, R., Measuring stigma in people with HIV: Psychometric assessment of the HIV stigma scale (2001) Res Nurs Health, 24, pp. 518-529. , https://onlinelibrary.wiley.com/doi/abs/https://doi.org/10.1002/Nur.10011; Luz, P.M., Torres, T.S., Almeida-Brasil, C.C., Marins, L.M.S., Bezerra, D.R.B., Veloso, V.G., Translation and validation of the short HIV stigma scale in Brazilian Portuguese (2020) Health Qual Life Outcomes, 18, pp. 1-12; Access to healthcare EPF’s survey – final report (2016) European Patient Forum, pp. 1-57; Abdulrahman, S.A., Rampal, L., Ibrahim, F., Radhakrishnan, A.P., Shahar, H.K., Othman, N., Mobile phone reminders and peer counseling improve adherence and treatment outcomes of patients on ART in Malaysia: a randomized clinical trial (2017) PLoS One, 12, pp. 1-16; Amberbir, A., Woldemichael, K., Getachew, S., Girma, B., Deribe, K., Predictors of adherence to antiretroviral therapy among HIV-infected persons: a prospective study in Southwest Ethiopia (2008) BMC Public Health, 8, pp. 1-9; Catalan, J., Tuffrey, V., Ridge, D., Rosenfeld, D., What influences quality of life in older people living with HIV? (2017) AIDS Res Ther, 14, pp. 1-10; Owen, G., Catalan, J., We never expected this to happen”: narratives of ageing with HIV among gay men living in London, UK (2012) Cult Heal Sex, 14 (1), pp. 59-72; Mahendradhata, Y., Ahmad, R.A., Lefèvre, P., Boelaert, M., Van Der Stuyft, P., Barriers for introducing HIV testing among tuberculosis patients in Jogjakarta, Indonesia: a qualitative study (2008) BMC Public Health, 8, pp. 1-10; Grim, B.J., Religious freedom: Good for what ails us? (2008) Rev Faith Int Aff, 6, pp. 3-7. , https://doi.org/10.1080/15570274.2008.9523330; García-Goñi, M., Nuño-Solinís, R., Orueta, J.F., Paolucci, F., Is utilization of health services for HIV patients equal by socioeconomic status? Evidence from the Basque country (2015) Int J Equity Health, 14 (1), pp. 1-10; Tran, B.X., Quality of life outcomes of antiretroviral treatment for HIV/AIDS patients in Vietnam (2012) PLoS One, 7, pp. 1-8; (2018) Ministry of Health. Annual Health Report, , https://pusdatin.kemkes.go.id/article/view/19042200004/situasi-umum-hiv-aids-dan-tes-hiv.html
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