Cumulative exposure characteristics of vegetable farmers exposed to Chlorpyrifos in Central Java – Indonesia; a cross-sectional study

Liem J.F., Mansyur M., Soemarko D.S., Kekalih A., Subekti I., Suyatna F.D., Suryandari D.A., Malik S.G., Pangaribuan B.

Doctoral Program, Faculty of Medicine Universitas Indonesia, Jakarta, 10430, Indonesia; Department of Occupational Health and Safety, Faculty of Medicine and Health Science Universitas Kristen Krida Wacana, Jakarta, 11510, Indonesia; Community Medicine Department, Faculty of Medicine Universitas Indonesia, Jakarta, 10320, Indonesia; Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, Jakarta, 10430, Indonesia; Department of Pharmacology and Therapeutics, Faculty of Medicine Universitas Indonesia, Jakarta, 10430, Indonesia; Department of Biology, Faculty of Medicine Universitas Indonesia, Jakarta, 10430, Indonesia; Eijkman Institute for Molecular Biology, National Research and Innovation Agency, Jalan Diponegoro No. 69, Kota Jakarta Pusat, Jakarta, Indonesia; Prodia Occupational Health Institute International, Jakarta, 10430, Indonesia


Abstract

Background: Agriculture is a major economic sector in Indonesia. Chemical pesticides are widely being used in agriculture for controlling pest. There is a growing concern that pesticide exposure, particularly chlorpyrifos (CPF) exposure, combined with other occupational characteristics that determine the level of exposure, can lead to further health impacts for farmers. Our objective was to evaluate the cumulative exposure characteristics among farmers exposed to CPF by using a validated algorithm. Methods: We conducted a cross-sectional study of 152 vegetable farmers aged 18–65 who actively used CPF for at least 1 year in Central Java, Indonesia. Subject characteristics were obtained using a structured interviewer-administered questionnaire, addressed for sociodemographic and work-related characteristics. The cumulative exposure level (CEL) was estimated as a function of the intensity level of pesticide exposure (IL), lifetime years of pesticide use and the number of days spraying per year. CEL was subsequently classified into two groups, high and low exposure groups. The difference in characteristics of the study population was measured using Chi-square, independent-t or Mann-Whitney test. Association between CEL and its characteristics variables were performed by multiple linear regression. Results: Seventy-one subjects (46.7%) were classified as the high exposure group. The use of multiple pesticide mixtures was common among our study population, with 94% of them using 2 or more pesticides. 73% reported direct contact with concentrated pesticides product, and over 80% reported being splashed or spilt during preparation or spraying activity. However, we found that the proportion of proper personal protective equipment (PPE) use in our subjects was low. Higher volume of mixture applied (p < 0.001) and broader acres of land (p = 0.001) were associated with higher cumulative exposure level, while using long-sleeved clothes and long pants (p < 0.05) during pesticide spraying were associated with lower cumulative exposure after adjusted for age and gender. Conclusions: These findings indicate an inadequate knowledge of using pesticides properly. Thus, we recommend comprehensive training on pesticide usage and encourage proper PPE to reduce the exposure level. © 2021, The Author(s). Exposure assessment; Exposure reduction; Occupational characteristics; Pesticide cumulative exposure; Work practices


Journal

BMC Public Health

Publisher: BioMed Central Ltd

Volume 21, Issue 1, Art No 1066, Page – , Page Count


Journal Link: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85107125504&doi=10.1186%2fs12889-021-11161-5&partnerID=40&md5=9fb7a1aa16134c6ee9e3e23e6280115f

doi: 10.1186/s12889-021-11161-5

Issn: 14712458

Type: All Open Access, Gold, Green


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