A clinical case series of COVID-19-associated acute limb ischemia: real-world situation

Surya S.P., Santoso R.M.

Primaya Hopsital Tangerang, Jl. MH. Thamrin no.3, Kebon Nanas, Cikokol, Tangerang, Indonesia; Department of Cardiology and Vascular Medicine, Primaya Hospital Tangerang, Tangerang, Indonesia


Background: COVID-19 was a trending topic all year long in 2020. Currently, it is not only a problem for a pulmonologist since it could cause complications to many other organs, including the cardiovascular system. Recent acute COVID-19 infection state has been associated with hypercoagulation and causing microthrombi called immunothrombus. Acute limb ischemia is one of the rare complications but organ-threatening. Unfortunately, unlike coronary artery disease, there is no recent guideline for cardiologists to diagnose and manage acute limb ischemia in pandemic situations Case presentation: This case series presented two patients with acute limb injury (ALI)-complicating COVID-19, with chief complaints of pain at their lower extremity. The first patient was an 80-year-old woman who was just dismissed from the hospital due to COVID-19. The distal part of her toe was cyanosed, and her motoric and sensory functions were partially reduced. She was treated with oral drug therapy due to unwillingness to be hospitalized. Interestingly, she had recovered by using oral drug therapy. The second case was a 54-years-old female with several comorbidities such as obesity, type 2 diabetes mellitus, hypertension, dyslipidemia, and chronic obstructive pulmonary disease. She had cyanosed foot and weak arterial pulsation. Unfortunately, she passed away due to acute respiratory distress syndrome. Conclusion: Several internal and external factors cause ALI treatment to be more challenging in the pandemic COVID-19 situation. The diagnosis and management of ALI in COVID-19 patients may not fully comply with the current guideline and are likely to be affected by local hospital regulations. Clinical follow-up might be an essential feature in treating ALI in COVID-19 patients. © 2021, The Author(s).

Acute limb ischemia; Case report; COVID-19; COVID-19-associated coagulopathy; Immunothrombus


Egyptian Heart Journal

Publisher: Springer Science and Business Media Deutschland GmbH

Volume 73, Issue 1, Art No 59, Page – , Page Count

Journal Link: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85108911942&doi=10.1186%2fs43044-021-00187-0&partnerID=40&md5=36564fd05a6c4aaf773ae70f71ca74fa

doi: 10.1186/s43044-021-00187-0

Issn: 11102608

Type: All Open Access, Gold, Green


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